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I'm familiar with the OWASP top 10, for web applications. Is there something simular for BizTalk applications?

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All standard secure coding principles apply. There is not a handy Top 10 list for specific vendor frameworks. –  schroeder Dec 12 '12 at 0:26
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up vote 2 down vote accepted

The OWASP Top 10 is not language specific; it is applicable for all web applications. The CWE Top 25 is the most generally used list for non-web applications. That's probably what you're looking for.

If you want something language specific, it'd be most helpful to look for a biztalk security guidance or a BizTalk hardening guide and also to obey common practices like treating all user input as malicious.

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