This is a typical Desktop ini file that normally saves the folder view settings such as the background image etc. If suspect some malware is executing on the Windows startup, it might be executing from
- Run and RunOnce keys in the registry
- Windows Services
- Windows drivers
- DLL hijacking (placing itself in a path that comes before the
- Registry key of the registered shell extensions
- Hidden file or shortcut in the startup folder
There might be other locations as well so your best bet is quarentine the machine and follow the standard procedure of malware cleanup. You will find plenty of examples on how to cleanup a malware infected machine on SE and other forums.