This KB article mentions an issue where signing or encrypting information may result in a network IO call to a Domain Controller. Apparently the RSACryptoServiceProvider's SignData and VerifyData ...
How do I sanitize LDAP input and prevent injection attacks? What LDAP injection scenarios are possible?
In the following C# example I'm querying AD's configuration container for Exchange overrides. If the domain name in unsanitised the end user could get LDAP to read a different object then intended. ...