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Yes. Exploitation of some very secure (and offline) networks have been accomplished via USB.

"noexec" and other features are not always enough to prevent keyloggers and other malicious devices from operating.

A reasonably good solution is to block all USB devices except those in a small whitelist of VIDs/SIDs (i.e. Vendor IDs and Serial Numbers). This gives you good security, as long as you guard who has access to the list of trusted VIDs and SIDs.

WINDOWS: One piece of software to do this on multiple versions of Windows is: http://www.newsoftwares.net/usb-block/

LINUX: See http://unix.stackexchange.com/questions/63199/how-to-disable-usb-devices-based-on-vendor-id-in-linux-environmenthttps://unix.stackexchange.com/questions/63199/how-to-disable-usb-devices-based-on-vendor-id-in-linux-environment

Yes. Exploitation of some very secure (and offline) networks have been accomplished via USB.

"noexec" and other features are not always enough to prevent keyloggers and other malicious devices from operating.

A reasonably good solution is to block all USB devices except those in a small whitelist of VIDs/SIDs (i.e. Vendor IDs and Serial Numbers). This gives you good security, as long as you guard who has access to the list of trusted VIDs and SIDs.

WINDOWS: One piece of software to do this on multiple versions of Windows is: http://www.newsoftwares.net/usb-block/

LINUX: See http://unix.stackexchange.com/questions/63199/how-to-disable-usb-devices-based-on-vendor-id-in-linux-environment

Yes. Exploitation of some very secure (and offline) networks have been accomplished via USB.

"noexec" and other features are not always enough to prevent keyloggers and other malicious devices from operating.

A reasonably good solution is to block all USB devices except those in a small whitelist of VIDs/SIDs (i.e. Vendor IDs and Serial Numbers). This gives you good security, as long as you guard who has access to the list of trusted VIDs and SIDs.

WINDOWS: One piece of software to do this on multiple versions of Windows is: http://www.newsoftwares.net/usb-block/

LINUX: See https://unix.stackexchange.com/questions/63199/how-to-disable-usb-devices-based-on-vendor-id-in-linux-environment

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Yes. Exploitation of some very secure (and offline) networks have been accomplished via USB.

"noexec" and other features are not always enough to prevent keyloggers and other malicious devices from operating.

A reasonably good solution is to block all USB devices except those in a small whitelist of VIDs/SIDs (i.e. Vendor IDs and Serial Numbers). This gives you good security, as long as you guard who has access to the list of trusted VIDs and SIDs.

WINDOWS: One piece of software to do this on multiple versions of Windows is: http://www.newsoftwares.net/usb-block/

LINUX: See http://unix.stackexchange.com/questions/63199/how-to-disable-usb-devices-based-on-vendor-id-in-linux-environment

Yes. Exploitation of some very secure (and offline) networks have been accomplished via USB.

"noexec" and other features are not always enough to prevent keyloggers and other malicious devices from operating.

A reasonably good solution is to block all USB devices except those in a small whitelist of VIDs/SIDs (i.e. Vendor IDs and Serial Numbers). This gives you good security, as long as you guard who has access to the list of trusted VIDs and SIDs.

Yes. Exploitation of some very secure (and offline) networks have been accomplished via USB.

"noexec" and other features are not always enough to prevent keyloggers and other malicious devices from operating.

A reasonably good solution is to block all USB devices except those in a small whitelist of VIDs/SIDs (i.e. Vendor IDs and Serial Numbers). This gives you good security, as long as you guard who has access to the list of trusted VIDs and SIDs.

WINDOWS: One piece of software to do this on multiple versions of Windows is: http://www.newsoftwares.net/usb-block/

LINUX: See http://unix.stackexchange.com/questions/63199/how-to-disable-usb-devices-based-on-vendor-id-in-linux-environment

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Yes. Exploitation of some very secure (and offline) networks have been accomplished via USB.

"noexec" and other features are not always enough to prevent keyloggers and other malicious devices from operating.

A reasonably good solution is to block all USB devices except those in a small whitelist of VIDs/SIDs (i.e. Vendor IDs and Serial Numbers). This gives you good security, as long as you guard who has access to the list of trusted VIDs and SIDs.