A privacy oriented DNS which doesn't use dnscrypt would at best have a feature that filters ads and prevents tracking by filtering slected domains. There are better ways to implement such privacy measures in my opinion and doing it at the DNS level can cause other problems.
Such a DNS would also not help you with DNS hijacking and allow anybody in the network or at the ISP to log the sites that you visit. This might or might not be a concern for you. But if it does matter then you should be using dnscrypt.
Another way to secure your DNS traffic would be to use a VPN and ensure there are no 'DNS leaks' when you are connected. i.e You are only using the DNS servers provided by your vpn which you will be connecting to over an encrypted connection.
My own reason for using dnscrypt is that I discovered my ISP has implemented a 'transparent DNS proxy'. This esentially forces everyone on the network to use ISP's DNS servers even when they have specifically configured other ones. This made me uneasy enough to want to look for a solution and dnscrypt fits the bill. My router that runs tomato firmware has this feature built in so I dont even have to install anything on my computer.