I have used the Notepad++ installer several times. However, it caught my eye that in one of the installer windows there is an option of:
Allow plugins to be loaded from %APPDATA%." Below it there is a warning that says "It could cause a security issue. Turn it on if you know what you are doing.
I came across this question whose answer left me with the impression that it has to do with User Access Control (UAC). However, I would like to get an expert voice in the issue.