I assume this question is about a short leave. In this case it might not be suitable to wipe the complete machine.
Dependent on the trust into you IT department, the following points may be good ideas:
- Browser caches, stored passwords, forms, ...
- Media Player caches
- Password Manager
- private files, including recycle bin. Of cause this does not wipe the data from HD,but makes it inconvenient to find.
- all other programs you use probably store information ... you will never get them all if you do it manually.
- unplug the SD card which is in the SD card reader and you always forget about :)
Actually, in most cases the IT department does not care. But you never know what a bored person might do with your computer. Moreover, probably the IT department is able to access the data on your computer at any time remotely.
For Windows 7 this question was already asked:
In Windows 10 there is also an out of the box soltuion. Goto
Start > Settings > Update & security > Recovery
taken from here:
Please feel free to edit the list.