Considering Linux's reputation for being somewhat immune to infections, and the fact that most malware are written with Windows as a target, is it safe to open possibly infected files on a Linux system?
I am aware of the more general ways of checking for an infection (rkhunter, chkrootkit, etc), but I also know these don't help if the infection somehow compromises them. What are the ways this can happen and how likely are these?
Since there is a difference in the structure and architecture between a PC and the Raspberry Pi, would using a Pi to open files and/or for forensic analysis add a layer of security?
I'm asking for systems air-gapped and isolated, so for the most part, only concerning infections and malware that might be hidden inside other files or passed through removable devices.