The short version is that you would want to install only the drivers you've approved. Then enable the following via Group Policy (or Local Group Policy). Your USB keyboard and USB mouse will adhere to this setting as will any USB device.
System\Device Installation\Device Installation Restrictions\
Prevent installation of removable devices
Description of this setting is as follows:
This policy setting allows you to prevent Windows from installing removable devices. A device is considered removable when the driver for the device to which it is connected indicates that the device is removable. For example, a Universal Serial Bus (USB) device is reported to be removable by the drivers for the USB hub to which the device is connected. This policy setting takes precedence over any other policy setting that allows Windows to install a device.
If you enable this policy setting, Windows is prevented from installing removable devices and existing removable devices cannot have their drivers updated. If you enable this policy setting on a remote desktop server, the policy setting affects redirection of removable devices from a remote desktop client to the remote desktop server.
If you disable or do not configure this policy setting, Windows can install and update device drivers for removable devices as allowed or prevented by other policy settings.
For a far more detailed explanation, see Step-By-Step Guide to Controlling Device Installation Using Group Policy. While it was last updated in 2007, the information is still applicable.
Mac and Ubuntu