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Is there a programmatic way to check if a given mobile application executable is malicious through some sort of lookup service? I have used Virustotal for desktop malware, does it work for mobile malware as well? Are there other standards for this sort of thing?

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Virus Total has malicious APKs as well, I'm sure you're aware of how to use their API if you've used them for desktop. You might also use Anubis.

Example:

https://www.virustotal.com/en/file/23a6384fc22e1dc10e49223292415c91cb7fc4540f7feae86c61165420009af7/analysis/

To declare an apk malicious that requires actual analysis. Some good resources to get started there might be Santoku or ARE.

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