The commenter, paj28, is correct: don't submit these to VirusTotal. Test them against the HIPS and AV systems you are specifically targeting in a VM-guest environment. I prefer using Vagrant along with the Packer and Boxcutter tools to "mock up" things in a lab.
Hyperion is great, but don't combine it with Pescrambler necessarily. You only need one cryptor, not two. What you ideally need is one cryptor and one packer, e.g., Hyperion and UPX. Try the various UPX formats and options: one will work after crypting. That would be the most-efficient and under-the-radar. Two cryptors or two packers is too many and "over the threshold".
Another factor is Meterpreter (or whatever baseline implant you are working from). It's not the best implant (some give away too much), especially not on Win32. It calls too many sensitive functions from too many W32 dependencies that are obviously malware. What you need is a different implant, such as Cobalt Strike Beacon or Silent Break Security Throwback. My favorite script circa Q42014 and Q1-2 2015 is veil_evasion.cna. It's in the official sources and probably PowerSploit, etc, but it can be loaded with a few others via this specific project from its original author -- https://github.com/HarmJ0y/cortana