Is there any type of DDoS where closing or taking full control of all port capabilities would be useful in mitigation of an attack?
The only thing I can think of is a broadcast storm or similar, where responses from the target are what's keeping the attack going. These are rare and almost invariably accidental, and there's an easier way to stop them than messing around with ports: just take the target system briefly offline.
Manual DDoS mitigation( taking control over the ports ) is no longer recommended due to DDoS attackers being able to circumvent DDoS mitigation software that is activated manually. Best practices for DDoS mitigation include having both anti-DDoS technology and anti-DDoS emergency response services